您的位置：首页 > 产品中心 > FeTMPyP-Calbiochem
FeTMPyP-Calbiochem
| 产品编号： | 4156859 |
| 规格： | Catalyzes the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions and at realistic dose-derived concentrations (kcat = 2.2 x 106M-1s- |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
FeTMPyP-Calbiochem
5,10,15,20-Tetrakis(N-methyl-4'-pyridyl)porphinato Iron (III) Chloride, Fe IIITMPyP(Cl)
基本信息
| Empirical Formula【经验(实验)分子式】 | C44H36Cl5FeN8 |
| Molecular weight | 909.92 |
| General description【一般描述】 | Catalyzes the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also decomposes superoxide radicals (O2•) catalytically. Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH•) radicals. FeTMPyP can also serve as a potential drug for reactive oxygen species (ROS) detoxification. Catalyzes the isomerization of peroxynitrite (ONOO–) to nitrate (NO3–) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O2·). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH·) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS). |
| Biochem/physiol Actions【生化/生理作用】 | Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions Primary Target Peroxynitrite (ONOO-) Product does not compete with ATP. Reversible: no Cell permeable: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C. |
| Other Notes【其他说明】 | Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493. Hunt, J.A., et al. 1997. Chem. Biol. 4, 845. Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243. Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735. Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med.46, 703. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥90% (TLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| color【颜色】 | brown |
| solubility【溶解性】 | water: 50 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 10 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
