E-Selectin, Human, Recombinant, CHO Cells

≥95% (SDS-PAGE)

100

lyophilized

Calbiochem^®

OK to freeze

<1 EU/μg Endotoxin (EU/μg of E-Selectin)

wet ice

−20℃

50 μg in Plastic ampoule

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.
Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLe^x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

Shown to bind to E-selectin ligands on U937 cells.

Toxicity: Standard Handling (A)

Lyophilized from Dulbecco′s PBS with stabilizer.

Reconstitute to 1 mg/ml with sterile H₂O.
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

11 - Combustible Solids

WGK 1