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Bromo-PEG2-acid
产品别名
1807503-92-9
Bromo-PEG2-acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C7H13BrO4 |
| Molecular weight | 241.08 |
| MDL number | MFCD28122969 |
| NACRES | NA.22 |
| Application【应用】 | Bromo-PEG2-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG2-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation. This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility. |
| Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
| Assay【测定】 | ≥95% |
| form【形式】 | liquid |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | BrCCOCCOCCC(O)=O BrCCOCCOCCC(O)=O |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
