Biotinylated-D-lysine TFA salt

C₁₆H₂₈N₄O₄S · C₂HF₃O₂

486.51

NA.22

Biotinylated D-lysine (BDL) can be used to conjugate a biotin handle into bacterial peptidoglycan (PG) for various applications. For example, Suzanne Walker and coworkers reported that penicillin-binding protein PBP4 of Staphylococcus aureus could use BDL to biotinylate Lipid I and Lipid II, facilitating assays to measure infamously low-abundance pools of cellular lipid-linked PG precursors. BDL provides a tool for studying other aspects of PG assembly including antibacterial development efforts.

Detection of Lipid-Linked Peptidoglycan Precursors by Exploiting an Unexpected Transpeptidase Reaction

100

powder or crystals

peptide synthesis

−20℃

O=C(O)C(F)(F)F.[O-]C([C@@H](CCCCNC(CCCC[C@@H]1[C@@](NC(N2)=O)([H])[C@@]2([H])CS1)=O)[NH3+])=O

10 mg in glass bottle

13 - Non Combustible Solids

WGK 3