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Anti-Tbr1 Antibody
| 产品编号： | 4155001 |
| 规格： | from chicken, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Tbr1 Antibody
T-box, brain, 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Tbr1 gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Tbr1, a putative transcription factor known to be expressed in post-mitotic neurons, has been found highly expressed in glutamatergic early-born cortical neurons. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region the Tbr1 derived protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. |
| Specificity【特异性】 | This antibody recognizes Tbr1. |
| Immunogen【免疫原】 | Epitope: Internal KLH-conjugated linear peptide corresponding to mouse Tbr1. |
| Application【应用】 | Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected Tbr1 in mouse frontal cortex tissue. Research Category Neuroscience Research Sub Category Developmental Neuroscience Anti-Tbr1 Antibody is an antibody against Tbr1 for use in WB, IH. |
| Quality【质量】 | Evaluated by Western Blot in human fetal brain tissue lysate. Western Blot Analysis: 0.025 µg/ml of this antibody detected Tbr1 on 10 µg of human fetal brain tissue lysate. |
| Physical form【外形】 | Affinity purified Purified chicken polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Human fetal brain tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | chicken |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse, human, rat |
| species reactivity (predicted by homology) | opossum (based on 100% sequence homology), bovine (based on 100% sequence homology), horse (based on 100% sequence homology), canine (based on 100% sequence homology), pig (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_033348 |
| UniProt accession no.【UniProt登记号】 | Q64336 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 68 kDa is observed; however, UniProtKB/Swiss-Prot entry Q64336 (TBR1_MOUSE) lists a mass of 73.941 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
