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Anti-Phospho-Bid (Ser65) Antibody
| 产品编号： | 4154795 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Phospho-Bid (Ser65) Antibody
BH3-interacting domain death agonist, p22 BID, BID
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. Bid induces ICE-like proteases and apoptosis. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the major proteolytic product p15 Bid translocates to mitochondria where it triggers cytochrome c release. |
| Specificity【特异性】 | Other species have not been tested. The antibody reacts with the 22 kDa phospho-Bid-S65 protein. |
| Immunogen【免疫原】 | Epitope: Ser65 |
| Application【应用】 | Anti-Phospho-Bid (Ser65) Antibody detects level of Phospho-Bid (Ser65) & has been published & validated for use in WB. Research Sub Category Apoptosis - Additional Research Category Apoptosis & Cancer |
| Quality【质量】 | Evaluated by Western Blot on Jurkat cell lysate treated with (+/-) insulin. Western Blot Analysis: A 1:100~500 dilution of this antibody detected phospho-Bid-S65 on jurkat cell lysate treated with (+/-) insulin. |
| Physical form【外形】 | Purified in PBS with 0.09% NaN3. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Western Blot:: Jurkat cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_001196.2 |
| UniProt accession no.【UniProt登记号】 | P55957-2 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 22 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
