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Anti-Olfactory Receptor 10G4 Antibody, clone 6C11.1
产品别名
Anti-Olfactory Receptor 10G4 Antibody, clone 6C11.1
Olfactory receptor OR11-278, Olfactory Receptor 10G4
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Olfactory receptor 10G4 (UniProt Q8NGN3; also known as Olfactory receptor OR11-278) is encoded by the OR10G4 gene (Gene ID 390264) in human. Olfactory receptors belong to the class A rhodopsin-like family of G protein-coupled receptors (GPCRs). The human genome contains approximately 800 odorant receptor (OR) genes that have been shown to exhibit high genetic variability. Human has approximately 400 intact ORs, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. Odorant molecule binding induces an OR conformational change and interaction with the olfactory-type G protein, initiating downstream signaling that eventually results in an action potential from the depolarized OR neuron to the brain. Olfactory receptor 10G4 is a 311-amino acid protein with 4 extracellular domains (a.a. 1-23, 74-98, 160-196, 258-268), 7 transmembrane segments (a.a. 24-44, 53-73, 99-119, 139-159, 197-216, 237-257, 269-289), and 4 cytoplasmic regions (a.a. 45-52, 120-138, 217-236, 290-311). |
Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to the C-terminal cytoplasmic tail of human Olfactory Receptor 10G4. |
Application【应用】 | Anti-Olfactory Receptor 10G4 Antibody, clone 6C11.1 is an antibody against Olfactory Receptor 10G4 for use in Western Blotting. |
Quality【质量】 | Evaluated by Western Blotting in human olfactory tissue lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected Olfactory Receptor 10G4 in 10 µg of human olfactory tissue lysate. |
Physical form【外形】 | Protein G Purified Format: Purified |
Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 6C11.1, monoclonal |
species reactivity | human |
technique(s) | western blot: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_001004462 |
UniProt accession no.【UniProt登记号】 | Q8NGN3 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~40 kDa observed. Target band size appears larger than the calculated molecular weight of 34.57 kDa due to glycosylation. |
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |