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Anti-MMP-9 Antibody, NT
| 产品编号： | 4154630 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-MMP-9 Antibody, NT
92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, macrophage gelatinase, matrix metallopeptidase 9, matrix metalloproteinase 9, type V collagenase
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell matrix interactions. MMPs are Zn2+ binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). MMP9, also known as gelatinase B, is a secreted enzyme which degrades the interstitial collagens, types I, II, and III and is produced by normal alveolar macrophages and granulocytes. |
| Specificity【特异性】 | The antibody recognizes human MMP-9. It does not cross react with MMP-1 or MMP-2. |
| Immunogen【免疫原】 | KLH-conjugated synthetic peptide corresponding to the N-terminus of MMP-9. Epitope: N-terminus |
| Application【应用】 | Research Category Cell Structure Anti-MMP-9 Antibody, N-terminus is an antibody against MMP-9 for use in WB. Research Sub Category MMPs & TIMPs |
| Quality【质量】 | Evaluated on a representative lot by Western blot using an HL-60 cell lysate supplemented with a PMA conditioned media. Western Blot Analysis: 0.5 µg/ml of this antibody detected MMP-9 on 10 µg of HL-60 plus PMA conditioned media. |
| Linkage【联系】 | Replaces: AB805 |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control HL-60 plus PMA conditioned media |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | canine, human |
| species reactivity (predicted by homology) | rat (based on 100% sequence homology), primate (based on 100% sequence homology), monkey (based on 100% sequence homology), dog (based on 100% sequence homology), horse (based on 100% sequence homology), pig (based on 100% sequence homology) |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_004985.2 |
| UniProt accession no.【UniProt登记号】 | P14780 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... MMP9(4318) |
产品说明
| Target description【目标描述】 | 92kDa (pro-form) and 88kDa (active form) |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
