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Anti-GABA B Receptor R1 Antibody
产品别名
Anti-GABA B Receptor R1 Antibody
GABA-B receptor, GABA-B receptor 1, GABAB, subunit 1c, gamma-aminobutyric acid (GABA) B receptor 1, gamma-aminobutyric acid B receptor 1, seven transmembrane helix receptor
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants. |
| Specificity【特异性】 | Reactivity with other species has not been determined. Cat. # AB2256 recognizes GABA B Receptor R1 (GABA B R1) |
| Immunogen【免疫原】 | Recombinant peptide (aa 972-991: PSEPPDRLSCDGSRVHLLYK) Epitope: C-Terminus interaction w/ ATF4 |
| Application【应用】 | Immunohistochemistry: Working dilution of 1:3,000 in free floating mouse brain tissue. Detect GABA B Receptor R1 using this Anti-GABA B Receptor R1 Antibody validated for use in WB, IH. Research Category Neuroscience Research Sub Category Neurotransmitters & Receptors |
| Quality【质量】 | Western Blotting: 1:1,000 dilution from a previous lot detected GABA B R1 on 10µg of rat brain lysate. |
| Physical form【外形】 | GST-Depleted Sera with 0.05% NaN3. |
| Analysis Note【分析说明】 | Control Rat brain lysates |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | guinea pig |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, rat, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_112290.2 |
| UniProt accession no.【UniProt登记号】 | Q9Z0U4 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~100-105 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20ºC from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
