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Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop
产品别名
Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop
CX3CR1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively (1-4). The seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by facktokine (6). CX3CR1 mediates leukocyte migration and adhesion. |
Immunogen【免疫原】 | Synthetic peptide from the extracellular loop of human CX3CR1. |
Application【应用】 | Anti-C-X-X-X-C Chemokine Receptor 1 Antibody, extracellular loop is an antibody against C-X-X-X-C Chemokine Receptor 1 for use in IH & WB. Western blot: 1:500 (THP cell lysate can be used as positive control and an approximately 50 kDa band can be detected) Immunohistochemistry in frozen sections Optimal working dilutions must be determined by end user. |
Physical form【外形】 | Format: Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NM_001337.3 |
UniProt accession no.【UniProt登记号】 | P49238 |
shipped in【运输】 | wet ice |
产品说明
【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |