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Anti-Anterior gradient protein 2 homolog Antibody, clone 7A10
产品别名
Anti-Anterior gradient protein 2 homolog Antibody, clone 7A10
anterior gradient homolog 2 (Xenopus laevis), anterior gradient 2 homolog, protein disulfide isomerase family A, member 17, Secreted cement gland protein XAG-2 homolog, anterior gradient protein 2 homolog, secreted cement gland homolog, anterior gradient
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Anterior gradient protein 2 homolog (AGR2) (also known as secreted cement gland protein XAG-2 homolog) is thought to be a metastasis-inducing protein in breast cancer models and may be used as a means of detecting the outcome of hormonally treated patients with breast cancer. AGR2 may also play an important role in intestinal mucus production. Recent researched has also linked AGR2 to metastasis. Lower levels of AGR expression in prostate cancer may be highly predictive of the reoccurrence of disease even after a prostatectomy. |
| Specificity【特异性】 | Specific for Anterior gradient protein 2 homolog and does not detect Anterior gradient protein 3 homolog. |
| Immunogen【免疫原】 | Linear peptide corresponding to a sequence unique to human Anterior gradient protein 2 homolog and not to human Anterior gradient protein 3 homolog. |
| Application【应用】 | Research Sub Category Tumor Markers Anti-Anterior gradient protein 2 homolog Antibody, clone 7A10 is an antibody against Anterior gradient protein 2 homolog for use in WB & IC. Research Category Apoptosis & Cancer Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC on primary carcinomas (Barraclough, D., et al. (2009). Am J Pathol. 175:1848–1857). |
| Quality【质量】 | Evaluated by Western Blot in MCF-7 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Anterior gradient protein 2 homolog in 10 µg of MCF-7 cell lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control MCF-7 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 7A10, monoclonal |
| species reactivity | human |
| technique(s) | immunocytochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_006399 |
| UniProt accession no.【UniProt登记号】 | O95994 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... AGR2(10551) |
产品说明
| Target description【目标描述】 | ~18 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
