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Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2
产品别名
Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2
annexin A1, chromobindin-9, annexin I (lipocortin I), Lipocortin I, calpactin-2, Calpactin II, annexin-1, Phospholipase A2 inhibitory protein, Annexin I, Calpactin-2, Annexin-13, Chromobindin-9
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Annexin A1 (ANXA1) is a calcium and phospholipid binding protein almost entirely restricted to microglia in the CNS. During the peripheral inflammatory response, Annexin A1 is instrumental in the phagocytosis of apoptotic leukocytes. Annexin A1 restores the ability of microglia to differentiate between apoptotic and non-apoptotic cells during inflammatory activation. Current research is geared towards using Annexin A1 as a therapeutic target in neuroinflammation. Annexin A1 has also been shown to be influential in cancer development and proliferation. |
| Immunogen【免疫原】 | Full length recombinant protein corresponding to human Annexin A1. Material obtained from the National Cancer Institute’s Clinical Proteomic Technologies for Cancer (CPTC) program |
| Application【应用】 | Immunohistochemistry Analysis: A previous lot was used by an independent laboratory in IH. (http://antibodies.cancer.gov/antibodies/detail/CPTC-ANXA1-2) Research Sub Category GPCR, cAMP/cGMP & Calcium Signaling This Anti-Annexin A1 Antibody, clone CPTC-ANXA1-2 is validated for use in WB, IH for the detection of Annexin A1. Research Category Signaling |
| Quality【质量】 | Evaluated by Western Blot in K562 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected Annexin A1 on 10 µg of K562 cell lysate. |
| Physical form【外形】 | Format: Purified Protein G Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control K562 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | CPTC-ANXA1-2, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_000691 |
| UniProt accession no.【UniProt登记号】 | P04083 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~ 39 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
