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Anti-Amyloid Precursor Protein Antibody, CT
产品别名
Anti-Amyloid Precursor Protein Antibody, CT
APP
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| Specificity【特异性】 | Recognizes Amyloid Precursor Protein (APP), C-terminal. Recognizes full length APP and C-terminal fragments resulting from cleavage by secretase. May react with APLP1 and APLP2. |
| Immunogen【免疫原】 | Epitope: C-terminus Nine amino acid peptide from the C-terminus of APP (YKFFEQMQN) |
| Application【应用】 | Detect Amyloid Precursor Protein using this Anti-Amyloid Precursor Protein Antibody, C-terminus validated for use in IC, IH, IP & WB. Research Category Neuroscience Research Sub Category Neurodegenerative Diseases Immunohistochemistry: 1:100-1:400 Immunocytochemistry on NTera2 and COS cell lines: 1:100-1:400 Western blot: 1:500-1:2000: The low abundance of full length APP in untreated cells means that poor response is seen with immunoblotting of whole cell lysates. We recommend that membrane fractions be prepared to increase the loading of APP as well as remove potential interferences from soluable proteins. NTera2, Cos7 and Hela cell membrane preparations are positive by western blots. Immunoprecipitation: 1:100-1:400. Optimal working dilutions must be determined by end user. |
| Physical form【外形】 | Unpurified Serum. Liquid in PBS with 0.02% azide. |
| Analysis Note【分析说明】 | Control Brain |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
| Legal Information【法律信息】 | CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | human, monkey |
| manufacturer/tradename | Chemicon® |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_000484.2 NM_201413.1 NM_201414.1 |
| UniProt accession no.【UniProt登记号】 | P05067 |
| shipped in【运输】 | dry ice |
| Gene Information | human ... APP(351) |
产品说明
| Storage and Stability【储存及稳定性】 | Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
