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5-Nitro-2-(3-phenylpropylamino)benzoic Acid-CAS 107254-86-4-Calbiochem
产品编号: | 4153424 |
规格: | Potent Cl- channel blocker (IC50 = 100 nM-100 μM), depending on channel subtype and assay method. |
CAS NO: | 107254-86-4 |
包装规格: | 10 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品价格查看更多规格...
产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4153424 | 10 MG | 1710 |
产品别名
107254-86-4
5-Nitro-2-(3-phenylpropylamino)benzoic Acid-CAS 107254-86-4-Calbiochem
NPPB, CaCC Blocker II, Calcium-Activated, TMEM16 Blocker II, ANO Blocker II, Anoctamin Blocker II
基本信息
Empirical Formula【经验(实验)分子式】 | C16H16N2O4 |
Molecular weight | 300.31 |
MDL number | MFCD00153851 |
General description【一般描述】 | Potent Cl– channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM). Potent Cl- channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM). |
Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Primary Target Cl⁻ channel blocker Target IC50: 100 nM-100 µM as Cl-channel blocker Cell permeable: no |
Warning【警告】 | Toxicity: Standard Handling (A) |
Other Notes【其他说明】 | Illek, B., et al. 1992. Am. J. Physiol.263, C644. Kirk, K., et al. 1992. J. Biol. Chem.267, 23475. Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun.163, 398. Wangermann, P., et al. 1986. Pflugers Arch.407, S128. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | solid |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze |
color【颜色】 | yellow |
solubility【溶解性】 | DMSO: 5 mg/mL warm ethanol: soluble |
shipped in【运输】 | ambient |
storage temp.【储存温度】 | 10-30℃ |
InChI | 1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20) |
InChI key | WBSMIPAMAXNXFS-UHFFFAOYSA-N |
packaging【包装】 | 10 mg in Plastic ampoule |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |