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3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride
产品别名
2088829-15-4
3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride
Bromo sulfonyl fluoride TMS-alkyne
Probe building block
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H12BrFO2SSi |
| Molecular weight | 335.26 |
| Application【应用】 | 3-Bromo-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. |
| Other Notes【其他说明】 | Technology Spotlight: Trifunctional Probe Building Blocks Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | powder or crystals |
| reaction suitability | reaction type: click chemistry |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
