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2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
产品别名
1450754-41-2
2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol
Probe building block
3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol
Hydroxyl diazirine alkyne
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C7H10N2O |
| Molecular weight | 138.17 |
| MDL number | MFCD29918290 |
| Application【应用】 | 2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. |
| Other Notes【其他说明】 | Technology Spotlight: Trifunctional Probe Building Blocks Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases In Situ Proteome Profiling and Bioimaging Applications of Small-Molecule Affinity-Based Probes Derived From DOT1L Inhibitors Reversible inhibitors arrest ClpP in a defined conformational state that can be revoked by ClpX association Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | liquid |
| density | 1.08 g/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | OCCC1(N=N1)CCC#C |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
