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米托蒽醌 二盐酸盐
Mitoxantrone hydrochloride
产品编号: | 4145535 |
规格: | United States Pharmacopeia (USP) Reference Standard |
CAS NO: | 70476-82-3 |
包装规格: | 400 MG |
产品类别: | 进口试剂 |
品牌: | USP |
优惠价: | 立即咨询 |
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
4145535 | 400 MG | 10290 |
产品别名
70476-82-3
米托蒽醌 二盐酸盐
Mitoxantrone hydrochloride
Mitoxantrone dihydrochloride
1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]-9,10-anthracenedione dihydrochloride
1,4-二羟基-5,8-双-[[2-[(2-羟乙基)氨基] 乙基] 氨基]-9,10-蒽二酮 二盐酸盐
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C22H28N4O6 · 2HCl |
Molecular weight | 517.40 |
MDL number | MFCD00242943 |
PubChem Substance ID【PubChem化学物质编号】 | 329750478 |
NACRES | NA.24 |
General description【一般描述】 | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. |
Biochem/physiol Actions【生化/生理作用】 | 米托蒽醌是一种细胞抑制性蒽二酮,可嵌入 DNA 中,通过稳定拓扑异构酶 II 与 DNA 的可裂解复合物,增加双链断裂的发生率。米托蒽醌还表现出广泛的免疫抑制活性,抑制各类淋巴细胞增殖并诱导抗原提呈 T 细胞凋亡。它在临床上用作抗白血病和实体瘤的化疗药物以及多发性硬化症的免疫系统调节剂。 |
Analysis Note【分析说明】 | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Other Notes【其他说明】 | USP issued SDS can be found here. Sales restrictions may apply. |
产品性质
grade【等级】 | pharmaceutical primary standard |
manufacturer/tradename | USP |
application(s) | pharmaceutical (small molecule) |
format【格式】 | neat |
SMILES string | Cl[H].Cl[H].OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 |
InChI | 1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H |
InChI key | ZAHQPTJLOCWVPG-UHFFFAOYSA-N |
Gene Information | human ... TOP2A(7153) |
安全信息
Pictograms【象形图】 | GHS08 |
Signal word【警示用语:】 | Danger |
Hazard Statements | H340 - H360 |
Precautionary Statements | P201 - P280 - P308 + P313 |
Hazard Classifications【危险分类】 | Muta. 1B - Repr. 1B |
Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
WGK | WGK 3 |