Concanavalin A, Canavalia ensiformis

MFCD00071069

Carbohydrate-binding protein that agglutinates various animal cells. Also known to restore the growth pattern of tumor cells to that of normal cells. T lymphocyte activator. Has binding sites for metal ions, α-D-mannose, and α-D-glucose.
Carbohydrate-binding protein that agglutinates various animal cells. Also known to restore the growth pattern of tumor cells to that of normal cells. T lymphocyte activator. Has binding sites for metal ions, α-D-mannose, and α-D-glucose. Has a pI of 4.5-5.5.

Toxicity: Harmful (C)

To dissolve, add Con A slowly to a solution of 10 mM HEPES buffered saline, 100 µM CaCl₂, pH 8.5. Allow the lectin to dissolve without agitation.

Following reconstitution, aliquot and freeze (-20°C) or add 0.08% NaN₃ and refrigerate (4°C). Stock solutions are stable for up to 6 months at -20°C or for up to 3 months at 4°C.

The agglutination activity is the lowest conc. to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25℃; requires type A human blood.

Gantner, F., et al. 1995. Hepatology 21, 190.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

lyophilized

≤20 μg/mL lectin agglutination activity (as determined from serial dilutions of a 1 mg/mL solution)

Calbiochem^®

OK to freeze

4.5 - 5.5

2-8℃

GHS08

Danger

H317 - H334 - H361

P201 - P202 - P280 - P302 + P352 - P304 + P340 + P312 - P308 + P313

Repr. 2 - Resp. Sens. 1 - Skin Sens. 1

11 - Combustible Solids

WGK 3