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Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
| 产品编号： | 4144290 |
| 规格： | PEG average Mn 5,000, PLGA average Mn 20,000, lactide:glycolide 50:50 |
| 包装规格： | 100 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide)
COOH-PEG-PLGA
Carboxylic acid PEG-PLGA
结构式
基本信息
| Linear Formula【线性分子式】 | H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nC2H3O2 |
| Application【应用】 | Carboxylic acid-poly(ethylene glycol)-b-poly(lactide-co-glycolide) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLGA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery. |
产品性质
| form【形式】 | powder or chunks |
| feed ratio【投料比】 | lactide:glycolide 50:50 |
| mol wt【分子量】 | PEG average Mn 5,000 (by NMR) PLGA average Mn 20,000 (by NMR) |
| color【颜色】 | white to tan |
| storage temp.【储存温度】 | −20℃ |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
