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Valrubicin
产品别名
56124-62-0
Valrubicin
Trifluoroacetyladriamycin 14-valerate
基本信息
| Empirical Formula【经验(实验)分子式】 | C34H36F3NO13 |
| Molecular weight | 723.64 |
| Biochem/physiol Actions【生化/生理作用】 | Valrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin. Valrubicin is converted intracytoplasmically into N-trifluoroacetyladriamycin, which interacts with topoisomerase II, stabilizing the complex between the enzyme and DNA and causing cell cycle arrest. |
产品性质
| form【形式】 | powder or crystals |
| storage temp.【储存温度】 | 2-8℃ |
| InChI | 1S/C34H36F3NO13/c1-4-5-9-21(40)49-13-20(39)33(47)11-16-24(19(12-33)51-22-10-17(27(41)14(2)50-22)38-32(46)34(35,36)37)31(45)26-25(29(16)43)28(42)15-7-6-8-18(48-3)23(15)30(26)44/h6-8,14,17,19,22,27,41,43,45,47H,4-5,9-13H2,1-3H3,(H,38,46)/t14?,17?,19-,22?,27?,33-/m0/s1 |
| InChI key | ZOCKGBMQLCSHFP-ZQUOIQDWSA-N |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H302 - H340 - H350 - H360F |
| Precautionary Statements | P201 - P202 - P264 - P280 - P301 + P312 + P330 - P308 + P313 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Carc. 1B - Muta. 1B - Repr. 1B |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
