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TNFSF8 human
| 产品编号： | 4141061 |
| 规格： | recombinant, expressed in E. coli, ≥80% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
TNFSF8 human
Tumor necrosis factor ligand superfamily member 8
CD153
CD30L
CD30LG
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. TNFSF8 was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin′s and some non-Hodgkin′s lymphomas. Recombinant human TNFSF8 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Physical form【外形】 | 0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol and 0.4 M Urea. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥80% (SDS-PAGE) |
| form【形式】 | liquid |
| mol wt【分子量】 | 22 kDa (195 aa, 63-234 aa + His Tag) |
| packaging【包装】 | pkg of 50 μg |
| concentration【浓度】 | 0.5 mg/mL |
| UniProt accession no.【UniProt登记号】 | P32971 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... TNFSF8(944) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
