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SETMAR, GST tagged human
| 产品编号： | 4140547 |
| 规格： | recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 20 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
SETMAR, GST tagged human
METNASE
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | SETMAR or SET domain and mariner transposase fusion gene is a nonhomologous end-joining repair protein that regulates genomic integration of exogenous DNA by opening chromatin and facilitating joining of DNA ends. SETMAR has histone methyltransferase activity and methylates ′Lys-4′ and ′Lys-36′ of histone H3. SETMAR also has DNA nicking activity and may play a role in DNA repair. Human Pso4 forms a stable complex with SETMAR that regulates Metnase function in DNA repair. SETMAR has sequence-specific DNA-binding activity and recognizes the 19-mer core of the 5′-terminal inverted repeats (TIRs) of the Hsmar1 element. |
| Physical form【外形】 | Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
| Preparation Note【制备说明】 | After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles. |
产品性质
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | 66-69 kDa |
| NCBI accession no.【NCBI登记号】 | BC011635 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... SETMAR(6419) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
