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Recombinant 2019-nCoV S1+S2 ECD (S-ECD) Protein with His tag
产品别名
Recombinant 2019-nCoV S1+S2 ECD (S-ECD) Protein with His tag
Spike glycoprotein
2019-nCoV S glycoprotein
2019-nCoV coronavirus spike Protein
COVID-19 S protein
cov spike Protein
2019-nCoV ncov spike Protein
产品性质
recombinant【重组】 | expressed in HEK 293 cells |
Quality Level【质量水平】 | 100 |
Assay【测定】 | >97% (SDS-PAGE) |
form【形式】 | liquid |
mol wt【分子量】 | 133.8 kDa |
impurities【杂质】 | <0.1 EU/μg protein (LAL test) |
UniProt accession no.【UniProt登记号】 | P0DTC2 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −70℃ |
Gene Information | SARS virus ... S(43740568) |
基本信息
General description【一般描述】 | The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates thisinteraction.The S protein plays key parts in the induction of neutralizing-antibody and T-cellresponses, as well as protective immunity. Recombinant SARS-COV-2 S1+S2 ECD (S-ECD) Protein with His tag (Wild type, pre-fusion state plus post-fusion state) is produced by HEK293 cells expression system. The target protein is expressed with sequence (Val11-Gln1208) of SARS-COV-2(2019-nCoV) S1+S2 ECD (S-ECD) (Accession #YP_009724390.1) fused with a 6XHis tag at the C-terminus. |
Biochem/physiol Actions【生化/生理作用】 | Measured by its binding ability in a functional ELISA. Immobilized Recombinant SARS-COV-2 Spike S1+S2 ECD-His at 2μg/mL (100 μL/well) can bind Recombinant Human ACE2 with a linear range of 0.15-9.92 ng/mL. |
产品说明
Storage and Stability【储存及稳定性】 | This product is stable at ≤ -70℃ for up to 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. Data presented is the available current product information and provided as-is. These products have not been tested or verified in any additional applications, sample types, including any clinical use. Experimental conditions must be empirically derived by the user. Our Antibody Guarantee only covers tested applications stated herein and conditions presented in our product information and is not extended to publications. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |