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PAK6, active, GST tagged human
| 产品编号： | 4139507 |
| 规格： | PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
PAK6, active, GST tagged human
PAK5
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | PAK6 is a Ser/Thr protein kinase that is a member of the PAK (p21-activated kinase) family that are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. PAK6 is highly expressed in the testis and prostate tissues and interacts with the androgen receptor (AR). In response to androgen, PAK6 cotranslocate into the nucleus with AR. PAK6 is weakly expressed in normal prostate epithelium but the expression is increased in primary and metastatic prostate cancer cells and is further increased in tumors that relapse after androgen deprivation therapy. |
| Physical form【外形】 | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note【制备说明】 | after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles |
| Legal Information【法律信息】 | PRECISIO is a registered trademark of sigma-aldrich Co. LLC |
产品性质
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| product line【产品线】 | PRECISIO® Kinase |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| Specific Activity | 116-158 nmol/min·mg |
| mol wt【分子量】 | ~110 kDa |
| NCBI accession no.【NCBI登记号】 | NM_020168 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PAK6(56924) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
