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PAD6, GST tagged human
| 产品编号： | 4139495 |
| 规格： | recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution |
| 包装规格： | 20 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
PAD6, GST tagged human
PADI6
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Peptidyl arginine deiminase 6 (PAD6) or PADI6 is a member of the peptidylarginine deiminases. It is expressed in oocytes and preimplantation embryos. The gene encoding this protein is localized on human chromosome 1p36. |
| Biochem/physiol Actions【生化/生理作用】 | Peptidyl arginine deiminases (PADs) convert arginine residues to citrulline residues in the presence of calcium ions. The PAD family members are thought to be involved in multiple sclerosis and rheumatoid arthritis pathophysiology, and they play a role in epidermis homeostasis. PAD6 is essential for formation of a novel oocyte-restricted fibrous structure, the cytoplasmic lattices (CPLs). PAD6/CPL superstructure plays a key role in regulating microtubule-mediated organelle positioning and movement. |
| Physical form【外形】 | Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Preparation Note【制备说明】 | after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles |
| Analysis Note【分析说明】 | This protein is not assayed for enzymatic activity. |
产品性质
| recombinant【重组】 | expressed in baculovirus infected Sf9 cells |
| Assay【测定】 | ≥70% (SDS-PAGE) |
| form【形式】 | buffered aqueous glycerol solution |
| mol wt【分子量】 | ~100 kDa |
| NCBI accession no.【NCBI登记号】 | NM_207421 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... PADI6(353238) |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
