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Milli-Mark® Anti-CD24-FITC Antibody, clone SN3
产品别名
Milli-Mark® Anti-CD24-FITC Antibody, clone SN3
Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen
基本信息
eCl@ss | 32160702 |
NACRES | NA.44 |
General description【一般描述】 | The CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002). CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002). |
Specificity【特异性】 | Antibody recognizes Human CD24 antigen. |
Immunogen【免疫原】 | Isolated membrane fraction of the pre-B leukemic cell line NALM-1. |
Application【应用】 | Research Sub Category Immunoglobulins & Immunology Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC. Research Category Inflammation & Immunology |
Quality【质量】 | Evaluated by flow cytometry using human PBMCs |
Physical form【外形】 | Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2. Protein A purified |
Analysis Note【分析说明】 | Control PBMCs |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
Legal Information【法律信息】 | MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | FITC conjugate |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | SN3, monoclonal |
species reactivity | human |
manufacturer/tradename | Milli-Mark® |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG1κ |
NCBI accession no.【NCBI登记号】 | NP_037362.1 |
UniProt accession no.【UniProt登记号】 | P25063 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | 35-45 kDa (Turni, 2002) |
Storage and Stability【储存及稳定性】 | Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |