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人FGF-23 ELISA试剂盒
Human FGF-23 ELISA Kit
产品编号: | 4119311 |
规格: | for cell culture supernatants, plasma, and serum samples |
包装规格: | 96 WELLS |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
人FGF-23 ELISA试剂盒
Human FGF-23 ELISA Kit
基本信息
NACRES | NA.32 |
General description【一般描述】 | This ELISA antibody pair detects Human FGF-23 The FGF23 (fibroblast growth factor 23) gene is mapped to human chromosome 12p13.32 and encodes a phosphaturic hormone secreted by osteocytes. FGF23 is a 30 kDa protein and is part of the FGF19 subfamily. |
Application【应用】 | For research use only. Not for use in diagnostic procedures. Please refer to the attached Protocolfor details. |
Biochem/physiol Actions【生化/生理作用】 | The protein fibroblast growth factor 23 (FGF23) mainly controls phosphate homeostasis and induces its excretion. Fgf23 maintains normal serum phosphate and calcium levels, by suppressing the action of sodium phosphate co-transporters and 25-hydroxyvitamin D 1-α-hydroxylase. Deficiency of the encoded protein causes chronic kidney disease. Leptin, a protein highly expressed in obesity is known influence the expression of this protein. Thus, higher FGF23 gene expression is observed in obese individuals. The FGF23 gene affects cardiac properties and is associated with cardiovascular risk factors such as alcoholism. |
Other Notes【其他说明】 | A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number. |
产品性质
species reactivity | human |
packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
technique(s) | ELISA: suitable |
input | sample type cell culture supernatant(s) sample type plasma sample type serum sample(s) |
assay range | inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.3 ng/ml |
Detection Method | colorimetric |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... FGF23(8074) |
安全信息
Pictograms【象形图】 | GHS05 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H290 |
Precautionary Statements | P234 - P390 |
Hazard Classifications【危险分类】 | Met. Corr. 1 |
Storage Class Code【储存分类代码】 | 8A - Combustible, corrosive hazardous materials |
WGK | WGK 3 |