Histone H2A (1-129) from Xanopus sp.

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Histone H2A (1-129) from Xanopus sp.

产品编号： 4119185

规格： recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
包装规格： 100 μG，250 μG
产品类别：进口试剂

品牌： Sigma-Aldrich
优惠价：立即咨询

产品价格
产品编号包装单位单价(元) 国内现货国外库存询价单
4119185 100 μG 3280
4119185 250 μG 7270

产品别名
Histone H2A (1-129) from Xanopus sp.
H2A GL101
H2a 615
H2A histone family member A
H2A histone family member B
基本信息
NACRES
NA.32
General description【一般描述】
H2A is a core component of nucleosome. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones. The octamer is composed of two of each histone H2A, H2B, H3, and H4. DNA accessibility is regulated via a complex set of post-translational modifications of these histones, also called histone code, and nucleosome remodeling. Histones H2A and H2B form a dimer. Histones H3 and H4 form a tetramer. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H3 undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, sumoylation, and biotinylation that are important for regulation of gene transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Physical form【外形】
Lyophilized powder. Recommended buffer is 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride, and 20% glycerol.
产品性质
biological source【生物来源】
Xenopus laevis
recombinant【重组】
expressed in E. coli
Assay【测定】
≥95% (SDS-PAGE)
form【形式】
lyophilized powder
mol wt【分子量】
13.9 kDa (1-129 aa)
packaging【包装】
pkg of 100 and 250 μg
UniProt accession no.【UniProt登记号】
Q16777
shipped in【运输】
dry ice
storage temp.【储存温度】
−70℃
Gene Information
human ... HIST2H2AC(8338)
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3

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产品编号	包装单位	单价(元)	国内现货	国外库存	询价单
4119185	100 μG	3280
4119185	250 μG	7270

NACRES	NA.32
General description【一般描述】	H2A is a core component of nucleosome. A nucleosome is the basic repeating unit of chromatin in which 146 base pairs of DNA wrap twice around an octamer of histones. The octamer is composed of two of each histone H2A, H2B, H3, and H4. DNA accessibility is regulated via a complex set of post-translational modifications of these histones, also called histone code, and nucleosome remodeling. Histones H2A and H2B form a dimer. Histones H3 and H4 form a tetramer. The combination of two H2A/H2B dimers and one H3/H4 tetramer create the nucleosome core. Histone H3 undergoes many modifications which include acetylation, phosphorylation, ubiquitylation, sumoylation, and biotinylation that are important for regulation of gene transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
Physical form【外形】	Lyophilized powder. Recommended buffer is 50 mM sodium phosphate, pH 7.2, containing 100 mM sodium chloride, and 20% glycerol.

biological source【生物来源】	Xenopus laevis
recombinant【重组】	expressed in E. coli
Assay【测定】	≥95% (SDS-PAGE)
form【形式】	lyophilized powder
mol wt【分子量】	13.9 kDa (1-129 aa)
packaging【包装】	pkg of 100 and 250 μg
UniProt accession no.【UniProt登记号】	Q16777
shipped in【运输】	dry ice
storage temp.【储存温度】	−70℃
Gene Information	human ... HIST2H2AC(8338)

Storage Class Code【储存分类代码】	13 - Non Combustible Solids
WGK	WGK 3