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Hexaminolevulinate hydrochloride
产品别名
140898-91-5
Hexaminolevulinate hydrochloride
5-Aminolevulinic acid hexyl ester hydrochloride
5-Aminolevulinic acid hexyl ester HAL hydrochloride
Hexyl 5-aminolevulinate hydrochloride
Hexvix
hal
P 1206
n-Hexyl 5-aminolevulinate hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H21NO3 · HCl |
| Molecular weight | 251.75 |
| MDL number | MFCD03695491 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825978 |
| Biochem/physiol Actions【生化/生理作用】 | Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 20 mg/mL, clear |
| storage temp.【储存温度】 | room temp |
| SMILES string | CCCCCCOC(CCC(CN)=O)=O.[H]Cl |
| InChI | 1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H |
| InChI key | LZYXPFZBAZTOCH-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
