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CD-14 human
| 产品编号： | 4117168 |
| 规格： | recombinant, expressed in CHO cells, 90-95% (SDS-PAGE) |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
CD-14 human
Cluster of differentiation 14
CD14
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macro¬pha¬ges and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50 kDa protein. |
| Physical form【外形】 | Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2 |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in 10 μl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in CHO cells |
| Assay【测定】 | 90-95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | 50.0 kDa |
| packaging【包装】 | pkg of 10 μg |
| impurities【杂质】 | Endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | P08571 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... CD14(929) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
