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BMP-3b human
| 产品编号： | 4116879 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE) |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
BMP-3b human
BMP3B
BIP
BMP-3b
Growth differentiation factor 10
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | GDF10 (growth differentiation factor 10) is a member of the bone morphogenetic protein (BMP) family and the TGF-β (transforming growth factor β) superfamily. It is expressed in femur, brain, lung, skeletal, muscle, pancreas and testis. Recombinant GDF10 protein was expressed in Escherichia coli and purified by using conventional chromatography techniques. |
| Biochem/physiol Actions【生化/生理作用】 | In rats, ectopic expression of GDF10 (growth differentiation factor 10) enhances osteoblast differentiation and also helps in bone formation. It plays a role in head formation in Xenopus embryos. After stroke, it is involved in axonal sprouting and functional recovery. The GDF10 gene is downregulated in lung cancer, mammary tumor, oral cancer and malignant mesothelioma. |
| Physical form【外形】 | 1 mg/mL in 10 mM sodium citrate (pH 3.5) containing 10% glycerol. |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (SDS-PAGE) |
| form【形式】 | liquid |
| mol wt【分子量】 | 12.5 kDa (111 aa, 369-478 aa) |
| packaging【包装】 | pkg of 100 μg |
| concentration【浓度】 | 1 mg/mL |
| UniProt accession no.【UniProt登记号】 | P55107 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... GDF10(2662) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
