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芹菜素

Apigenin
产品编号:4116450
规格:United States Pharmacopeia (USP) Reference Standard
CAS NO:520-36-5
包装规格:30 MG
产品类别:进口试剂
品牌:USP
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
411645030 MG3880
产品别名

520-36-5

芹菜素

Apigenin

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

4′,5,7-Trihydroxyflavone

4 ′,5,7-三羟基黄酮

5,7-二羟基-2-(4-羟基苯基)-4-苯并吡喃酮

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C15H10O5
Molecular weight
270.24
Beilstein
262620
MDL number
MFCD00006831
PubChem Substance ID【PubChem化学物质编号】
329749048
NACRES
NA.24
General description【一般描述】
Flavonoids belong to polyphenolic class of compounds. They play crucial role in biological activities which include tumor growth inhibition and chemoprevention. Apigenin is a plant flavonoid mostly used to inhibit ornithine decarboxylase activity and skin tumor.
Application【应用】
It may be used as internal standard for determining peurarin and its metabolites, using LC-ESI-MS/MS, in blood and urine of rats.
Biochem/physiol Actions【生化/生理作用】
一种植物类黄酮,研究发现它通过在G2/M阶段阻止细胞周期来抑制细胞增殖。通过细胞周期停滞和诱导凋亡来抑制生长似乎与p53的诱导有关。通过抑制蛋白激酶C和由此导致的癌基因表达抑制来抑制PMA介导的肿瘤促进。研究还报道了抑制拓扑异构酶ⅰ催化的脱氧核糖核酸再连接和增强间隙连接细胞间通讯。
Analysis Note【分析说明】
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​
Other Notes【其他说明】
USP issued SDS can be found here.
Sales restrictions may apply.
产品性质
grade【等级】
pharmaceutical primary standard
manufacturer/tradename
USP
mp
>300 ℃ (lit.)
application(s)
pharmaceutical (small molecule)
format【格式】
neat
storage temp.【储存温度】
−20℃
SMILES string
Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
InChI
1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
InChI key
KZNIFHPLKGYRTM-UHFFFAOYSA-N
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
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