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产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody product type | primary antibodies |
clone【克隆】 | monoclonal |
form【形式】 | liquid |
concentration【浓度】 | 0.4 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:200 |
UniProt accession no.【UniProt登记号】 | P67809 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... YBX1(4904) |
基本信息
General description【一般描述】 | This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015] |
Immunogen【免疫原】 | A synthesized peptide derived from human YB-1/YBX1 |
Physical form【外形】 | Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |