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产品别名
Anti-WNT4 antibody produced in rabbit
SERKAL
WNT-4
WNT4
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 32 39 |
species reactivity | rat, human, mouse |
concentration【浓度】 | 1.28 mg/ml |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | P56705 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... WNT4(54361) |
基本信息
General description【一般描述】 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. |
Immunogen【免疫原】 | Recombinant fusion protein containing a sequence corresponding to amino acids 122-351 of human WNT4 (NP_110388.2). |
Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |