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Anti-Tryptophan hydroxylase 2 Antibody
| 产品编号： | 4115630 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Tryptophan hydroxylase 2 Antibody
tryptophan hydroxylase 2, Tryptophan 5-monooxygenase 2, Neuronal tryptophan hydroxylase, tryptophan 5-hydroxylase 2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Tryptophan hydroxylase 2 (TPH2) is preferentially expressed in the brain and is thought to play an important role in serotonin synthesis. Recent research has actually associated high levels of TPH2 with risk of suicide. Misfolding of TPH2 may be the cause of a loss of serotonin neuronal function in Parkinson’s disease. Detection and screening of particular mutations in TPH2 has been cited as an approach toward predicting patient sensitivity to potential antidepressant therapies and even the possibility of diagnosis of behavioral disorders. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human Tryptophan hydroxylase 2. |
| Application【应用】 | Research Sub Category Signaling Neuroscience Research Category Neuroscience Anti-Tryptophan hydroxylase 2 Antibody detects level of Tryptophan hydroxylase 2 & has been published & validated for use in WB, IH(P). Immunohistochemistry Analysis: 1:400 dilution from a previous lot detected Tryptophan hydroxylase 2 in rat cerebral cortex tissue. |
| Quality【质量】 | Evaluated by Western Blotting in rat brain tissue lysate. Western Blotting Analysis: 0.2 µg/mL of this antibody detected Tryptophan hydroxylase 2 on 10 µg of rat brain tissue lysate. |
| Physical form【外形】 | Affinity purified Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Rat brain tissue lysate |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, rat |
| species reactivity (predicted by homology) | mouse (immunogen homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_775567 |
| UniProt accession no.【UniProt登记号】 | Q8IWU9 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~56 kDa observed |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
