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Anti-TRAPPC1 Antibody
产品编号: | 4115493 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-TRAPPC1 Antibody
TRAPPC-1, Trafficking protein particle complex subunit 1, BET5 homolog, Multiple myeloma protein 2, MUM-2, MUM2
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | TRAPPC1 is one part of a larger protein complex called the TRAPP (transport protein particle) complex vital to Golgi function and transport. TRAPPC1 is localized to the Golgi and endoplasmic reticulum. Vesicle-mediated transport is a process carried out by virtually all cells and is required for the proper targeting and secretion of proteins. As such, there are numerous proteins involved to ensure that the proteins are properly transported, targeted, tethered, and localized. The TRAPP complex is just one such complex but it is one of the most studied. Mutations in TRAPPC proteins can lead to serious disorders including muscular dystrophy and myopathy such as that seen with mutations associated with TRAPPC11 (a related gene to TRAPPC1). |
Immunogen【免疫原】 | Epitope: Near C-terminus KLH-conjugated linear peptide corresponding to the Near C-terminus of Human TRAPPC1. |
Application【应用】 | Western Blotting Analysis: 0.25 µg/mL from a representative lot detected TRAPPC1 in 5 µg of mouse brain tissue lysate. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TRAPPC1 in human cerebral cortex, cerebellum, and kidney. Research Category Neuroscience Neuroscience This Anti-TRAPPC1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of TRAPPC1. Research Sub Category Ion Channels & Transporters Neurotransmitters & Receptors |
Quality【质量】 | Evaluated by Western Blotting in TRAPPC1 transfected HEK293T cell lysate. Western Blotting Analysis: 0.25 µg/mL of this antibody detected TRAPPC1 in 5 µg of TRAPPC1 transfected HEK293T cell lysate. |
Physical form【外形】 | Purified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Antigen Affinity Purified |
Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human |
species reactivity (predicted by homology) | monkey (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001160093 |
UniProt accession no.【UniProt登记号】 | Q9Y5R8 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~19 kDa observed. The endogenous band appears at ~31kDa (mouse brain) while the transfected band appears at ~19kDa |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |