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Anti-RIPK1 Antibody
产品编号: | 4113719 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-RIPK1 Antibody
Receptor-interacting serine/threonine-protein kinase 1, RIPK1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Receptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis). |
Immunogen【免疫原】 | RIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1. Epitope: Near N-terminus |
Application【应用】 | Research Sub Category Apoptosis - Additional This Anti-RIPK1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of RIPK1. Research Category Apoptosis & Cancer Immunohistochemistry Analysis (IHC): 2.5 μg/mL from a representative lot detected RIPK1 in mouse kidney tissue. |
Quality【质量】 | Evaluated by Western Blotting in rat kidney tissue lysate. Western Blotting Analysis (WB): 1 μg/mL of this antibody detected RIPK1 in rat kidney tissue lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide. Antigen Affinity Purified |
Other Notes【其他说明】 | Concentration: Please refer to lot specific datasheet. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
UniProt accession no.【UniProt登记号】 | Q13546 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~75 kDa observed. Uncharacterized bands may be observed in some lysate(s). |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |