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Anti-Proopiomelanocortin/POMC antibody produced in goat
| 产品编号： | 4113171 |
| 规格： | affinity isolated antibody, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Proopiomelanocortin/POMC antibody produced in goat
Anti-ACTH
Anti-CLIP
Anti-POC
基本信息
| MDL number | MFCD00162087 |
| NACRES | NA.41 |
| General description【一般描述】 | Proopiomelanocortin (POMC) is a pro-peptide and multifunctional precursor protein for melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone ACTH. The POMC gene is mapped to human chromosome 2p23.3. It is expressed in skin, pituitary gland, and tissues of the immune system. |
| Immunogen【免疫原】 | Peptide with sequence C-NAIIKNAYKKGE from the C Terminus of the protein sequence according to NP_000930.1; NP_001030333.1. |
| Biochem/physiol Actions【生化/生理作用】 | Proopiomelanocortin (POMC) expression is regulated by hypermethylation of the upstream CpG-rich island in the gene. Mutations in the POMC gene are implicated in adrenocorticotropic hormone (ACTH) deficiency. Adrenal insufficiency and obesity are correlated to loss of function mutations in POMC. |
| Features and Benefits【特点和优势】 | Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. |
| Physical form【外形】 | Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | rat, mouse, human |
| technique(s) | immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
| UniProt accession no.【UniProt登记号】 | P01189 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... POMC(5443) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
