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Anti-PREX2 (N-terminal) antibody produced in rabbit biotin conjugated
产品别名
Anti-PREX2 (N-terminal) antibody produced in rabbit biotin conjugated
DKFZp686A20267
产品性质
| biological source【生物来源】 | rabbit |
| conjugate【偶联物】 | biotin conjugate |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | 182 kDa |
| species reactivity (predicted by homology) | canine, rabbit, pig, bovine, mouse, horse, rat, human |
| concentration【浓度】 | 0.5 mg/mL |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PREX2(80243) |
基本信息
| General description【一般描述】 | PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. PREX2 mediates the activation of RAC1 in a PI3K-dependent manner. PREX2 may be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase. |
| Immunogen【免疫原】 | Synthetic peptide directed towards the N-terminal region of Human PREX2 |
| Sequence【序列】 | Synthetic peptide located within the following region: ERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVH |
| Physical form【外形】 | Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | nwg |
