Anti-Phospho-MAPK14-Y182 antibody produced in rabbit

rabbit

100

affinity isolated antibody

primary antibodies

polyclonal

buffered aqueous solution

29
34
35
41

human, mouse, rat

6.49 mg/ml

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

Q16539

wet ice

−20℃

human ... MAPK14(1432)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

A synthetic phosphorylated peptide around Y182 of human MAPK14 (NP_620581.1).

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Store at -20℃. Avoid freeze / thaw cycles.

12 - Non Combustible Liquids

WGK 1