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Anti-Peripherin-2 Antibody, clone 6B10.1
产品别名
Anti-Peripherin-2 Antibody, clone 6B10.1
Peripherin-2, Retinal degeneration slow protein, Tetraspanin-22, Tspan-22
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Peripherin-2 (PRPH2) is also called Retinal degeneration slow protein (RDS) and Tetraspanin-22 (Tspan-22). Peripherin-2 is a critical factor in ocular disk morphogenesis and possibly functions as an adhesion molecule helping to stabilize and compact outer segment disks, to help maintain curvature of the rim. Peripherin-2 is expressed in the photoreceptors of the retina and in the rim of rod outer segment (ROS) disks. Peripherin-2 defects are found in different retinal diseases including cone-rod dystrophy, retinitis pigmentosa, and macular degeneration. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to the cytoplasmic domain of human Peripherin-2. Epitope: Cytoplasmic domain |
| Application【应用】 | Anti-Peripherin-2 Antibody, clone 6B10.1 is a highly specific mouse monoclonal antibody, that targets Peripherin & has been tested in western blotting & IHC. Research Category Neuroscience Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Peripherin-2 in 10 µg of human retina tissue lysate. Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Peripherin-2 in human retina tissue. Research Sub Category Developmental Signaling |
| Quality【质量】 | Evaluated by Western Blotting in mouse eye tissue lysate. Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Peripherin-2 in 10 µg of mouse eye tissue lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 6B10.1, monoclonal |
| species reactivity | human, rat, mouse |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_000313 |
| UniProt accession no.【UniProt登记号】 | P23942 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~35 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
