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Anti-Periostin Antibody (C-term)
产品别名
Anti-Periostin Antibody (C-term)
Periostin, PN, Osteoblast-specific factor 2, OSF-2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Periostin, also known as PN, or Osteoblast-specific factor 2 (OSF-2), and encoded by the gene POSTN/OSF2, is a secreted extracellular matrix protein that appears to be involved in inducing cell attachment and spreading as well as cell adhesion. In bone, Periostin enhances mineralization and assists in the incorporation of BMP1 protein into the fibronectin extracellular matrix of connective tissues. Periostin is preferentially expressed in periosteum and periodontal ligaments but can also be found expressed in developing heart and other tissues. Periostin is also over expressed in many cancers where is contributes to a growth-supportive role for such cancers and also aids in chemoresistance for cancers cells through the activation of the PI3K/Akt/surviving pathway. |
| Specificity【特异性】 | This antibody detects a subset of splice variants of Periostin. |
| Immunogen【免疫原】 | A 188-amino acid bacterial fusion protein from the C-terminal region of mouse periostin. Epitope: C-terminus |
| Application【应用】 | Research Category Cell Structure Anti-Periostin Antibody (C-term) is an antibody against Periostin (C-term) for use in western blotting. Research Sub Category Adhesion (CAMs) |
| Quality【质量】 | Evaluated by Western Blotting in mouse lung tissue lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected Periostin in 10 µg of mouse lung tissue lysate. |
| Physical form【外形】 | Affinity purified Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | mouse |
| concentration【浓度】 | 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_001185694 |
| UniProt accession no.【UniProt登记号】 | Q62009 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~80-85 kDa observed. Multiple splice variants detected. |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
