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Anti-Pcsk1n (N-terminal) antibody produced in rabbit

产品编号:4111979
规格:affinity isolated antibody
包装规格:100 μL
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4111979100 μL5250
产品别名

Anti-Pcsk1n (N-terminal) antibody produced in rabbit

SAAS

产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
mol wt【分子量】
28 kDa
species reactivity (predicted by homology)
rat, canine, human, mouse, guinea pig, bovine
concentration【浓度】
0.5 mg/mL
technique(s)
western blot: 1 μg/mL
NCBI accession no.【NCBI登记号】
NM_019279
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
Gene Information
human ... PCSK1N(27344)
基本信息
General description【一般描述】
Pcsk1n may function in the control of the neuroendocrine secretory pathway. It is proposed to be a specific endogenous inhibitor of PCSK1. ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi. It reduces the activity of the 87 kDa form but not the autocatalytically derived 65 kDa form of PCSK1. Subsequent processing of proSAAS may eliminate the inhibition. Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin. Pcsk1n may control the intracellular timing of PCSK1 rather than its total level of activity.
Immunogen【免疫原】
Synthetic peptide directed towards the N-terminal region of Rat Pcsk1n
Sequence【序列】
Synthetic peptide located within the following region: STPLRLRRAVPRGEAAGAVQELARALAHLLEAERQERARAEAQEAEDQQA
Physical form【外形】
Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide
产品说明
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
10 - Combustible liquids
WGK
nwg
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