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Anti-P-Rex1 Antibody, clone 6F12
产品别名
Anti-P-Rex1 Antibody, clone 6F12
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,4,5)-dependent Rac exchanger 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1protein (P-Rex1) is a guanine nucleotide exchange factor, which is predominantly expressed in the brain and leucocytes. It exchanges GDP for GTP in Rac 1, resulting in activation of Rac and its downstream signaling molecules that mediate such cellular processes as axon migration and differentiation. |
| Immunogen【免疫原】 | Linear peptide corresponding to human P-Rex 1. |
| Application【应用】 | Western Blot Analysis: A representative lot was used by an independent laboratory to detect P-Rex 1 in PC3 cell lysate (Donald, S.,et al., 2010.), bone-marrow-derived neutrophils from mice (Qin, J., et al., 2009.), and mouse brain sections. (Welch, H, et al., 2005.) Research Sub Category Apoptosis - Additional Research Category Apoptosis & Cancer This Anti-P-Rex1, clone 6F12 is validated for use in IP, WB, IH for the detection of P-Rex1. |
| Quality【质量】 | Evaluated by Western Blot in THP-1 cell lysate. Western Blot Analysis: A 1:1,000 dilution of this antibody detected P-Rex 1 in 10 µg of THP-1 cell lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control THP-1 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 6F12, monoclonal |
| species reactivity | human |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_065871 |
| UniProt accession no.【UniProt登记号】 | Q8TCU6 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... PREX1(57580) |
产品说明
| Target description【目标描述】 | ~186 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
