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Anti-Nhe-1 (ab2) antibody produced in rabbit
产品编号: | 4110999 |
规格: | affinity isolated antibody, buffered aqueous solution |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-Nhe-1 (ab2) antibody produced in rabbit
Anti-Solute carrier family 9 (sodium/hydrogen exchanger), member 1
Anti-SLC9A1
Anti-Sodium-hydrogen exchanger 1
Anti-Solute carrier family 9 member 1
Anti-Na+/H+ antiporter
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
species reactivity | mouse, rat, human |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
UniProt accession no.【UniProt登记号】 | P19634 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... SLC9A1(6548) |
基本信息
General description【一般描述】 | SLC9A1 (solute carrier family 9 member A1)/Na+/H+ exchanger 1 (NHE1), a plasma membrane transporter, is mapped to human chromosome 1p36. It belongs to the NHE family. NHE1 is abundantly expressed in all organisms. |
Immunogen【免疫原】 | a 17 amino acid peptide near the center of the human Nhe-1. |
Application【应用】 | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Immunohistochemistry (1 paper) Anti-Nhe-1 (ab2) antibody has been used in immunohistochemistry. |
Biochem/physiol Actions【生化/生理作用】 | Na+/H+ exchanger 1 (NHE1) modulates intracellular pH by exchanging a proton for an extracellular sodium ion and affects cell growth, proliferation, migration and apoptosis. It plays a major role in cancers including breast cancer, hepatocellular carcinoma, colon cancer, pancreatic ductal adenocarcinoma, prostate cancer, cervical cancer and neuroblastoma. |
Linkage【联系】 | The action of this antibody can be blocked using blocking peptide SBP4379. |
Physical form【外形】 | Solution in phosphate buffered saline containing 0.02% sodium azide |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 2 |