您的位置:首页 > 产品中心 > Anti-NFATC4 antibody produced in rabbit
Anti-NFATC4 antibody produced in rabbit
产品别名
Anti-NFATC4 antibody produced in rabbit
Anti-nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
基本信息
NACRES | NA.41 |
General description【一般描述】 | NFATC4 forms a part of a DNA-binding transcription complex that consists of inducible cytosolic and nuclear components. NFATC4 is involved in modulating neurotrophin-mediated synaptic plasticity and can also induce interleukins 2 and 4. p38 Mitogen-activated protein (MAP) kinases can regulate NFATC4 phosphorylation. Rabbit Anti-NFATC4 antibody recognizes canine, bovine, human, mouse, and rat NFATC4. |
Immunogen【免疫原】 | Synthetic peptide directed towards the middle region of human NFATC4 |
Application【应用】 | Rabbit Anti-NFATC4 antibody can be used for western blot (1.25μg/ml) and IHC (4-8μg/ml) applications. |
Biochem/physiol Actions【生化/生理作用】 | NFATC4 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. NFATC4 plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. |
Sequence【序列】 | Synthetic peptide located within the following region: GEELVLTGSNFLPDSKVVFIERGPDGKLQWEEEATVNRLQSNEVTLTLTV |
Physical form【外形】 | Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | IgG fraction of antiserum |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 95 kDa |
species reactivity | rat, human, bovine, rabbit, mouse, guinea pig, dog, horse |
concentration【浓度】 | 0.5 mg - 1 mg/mL |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_001129494 |
UniProt accession no.【UniProt登记号】 | Q14934 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... NFATC4(4776) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |