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Anti-NETO1 Antibody
产品编号: | 4110856 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-NETO1 Antibody
Neuropilin and tolloid-like protein 1, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Neuropilin and tolloid-like protein 1, also known as Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1, and encoded by the gene name NETO1 or BTCL1, is involved in the development and/or maintenance of neuronal circuitry. It is a type I transmembrane protein that is expressed in the brain and retina. NETO1 contains one LDL-receptor class A domain and two CUB domains and is either membrane-bound or secreted. It has three alternatively spliced isoforms, the first two of which are retina-specific and the third of which is found in both retina and brain tissue. Furthermore, as an accessory subunit of the neuronal Nmethyl- D-aspartate receptor (NMDAR), it regulates long-term NMDA receptor-dependent synaptic plasticity and cognition, at least in the context of spatial learning and memory. |
Immunogen【免疫原】 | KLH-conjugated synthetic peptide corresponding to the C-terminus of human NETO1. Epitope: C-terminus |
Application【应用】 | Research Category Neuroscience Research Sub Category Developmental Neuroscience Anti-NETO1 Antibody detects level of NETO1 & has been published & validated for use in NETO1. |
Quality【质量】 | Evaluated by Western Blotting in human lung tissure lysate. Western Blotting Analysis: 2 μg/mL of this antibody detected NETO1 in human lung tissure lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. Antigen Affinity Purified |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | human |
technique(s) | western blot: suitable |
UniProt accession no.【UniProt登记号】 | Q8TDF5 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~55 kDa observed. Uncharacterized bands may be observed in some lysate(s). |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
WGK | WGK 2 |