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产品别名
Anti-MMP1 antibody produced in rabbit
CLGN
MMP1
CLG
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | 54 |
species reactivity | human |
concentration【浓度】 | 1.08 mg/ml |
technique(s) | western blot: 1:500-1:2000 |
UniProt accession no.【UniProt登记号】 | P03956 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... MMP1(4312) |
基本信息
General description【一般描述】 | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
Immunogen【免疫原】 | Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human MMP1 (NP_002412.1). |
Physical form【外形】 | PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
产品说明
Storage and Stability【储存及稳定性】 | Store at -20℃. Avoid freeze / thaw cycles. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |