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Anti-mHUMMR Antibody
产品编号: | 4110229 |
规格: | from rabbit, purified by affinity chromatography |
包装规格: | 100 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Anti-mHUMMR Antibody
Hypoxia up-regulated mitochondrial movement regulator
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | Hypoxia up-regulated mitochondrial movement regulator (HUMMR), a novel mitochondria protein, is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 α (HIF-1α). HUMMR interacts with Miro-1 and Miro-2, mitochondrial proteins that are critical for mediating mitochondrial transport. Knockdown of HUMMR or HIF-1 function in neurons exposed to hypoxia markedly reduces mitochondrial content in axons. |
Specificity【特异性】 | This antibody recognizes mouse HUMMR protein |
Immunogen【免疫原】 | Linear peptide corresponding to mouse HUMMR. Epitope: Unknown |
Application【应用】 | Anti-mHUMMR Antibody is an antibody against mHUMMR for use in WB. Research Category Neuroscience Research Sub Category Neurodegenerative Diseases |
Quality【质量】 | Evaluated by Western Blot in mouse testis lysate. Western Blot Analysis: 1 µg/mL of this antibody detected HUMMR on 10 µg of mouse testis lysate. |
Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
Analysis Note【分析说明】 | Control Mouse testis lysate |
Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | affinity isolated antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
purified by【纯化方式】 | affinity chromatography |
species reactivity | mouse |
technique(s) | western blot: suitable |
NCBI accession no.【NCBI登记号】 | NP_080634 |
UniProt accession no.【UniProt登记号】 | Q8VI64 |
shipped in【运输】 | wet ice |
产品说明
Target description【目标描述】 | ~ 45 kDa observed. 50 kDa calculated. |
Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |