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Anti-Ly-6G Antibody (mouse), PerCP-Cy5.5, clone 1A8
产品别名
Anti-Ly-6G Antibody (mouse), PerCP-Cy5.5, clone 1A8
Lymphocyte antigen 6G, Ly-6G, Ly-6G.1
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
General description【一般描述】 | The 1A8 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils. In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. |
Immunogen【免疫原】 | Immunogen information for this antibody is proprietary information. |
Application【应用】 | This rat monoclonal antibody Anti-Ly-6G (mouse), PerCP-Cy5.5 & clone 1A8 validated for use in Flow Cytometry for the detection of Ly-6G. Research Category Inflammation & Immunology |
Quality【质量】 | The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.25 µg of this antibody detected Ly-6G in one million C57Bl/6 bone marrow cells. |
Physical form【外形】 | Size Exclusion Chromatography Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | rat |
conjugate【偶联物】 | PerCP-Cy5.5 |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | 1A8, monoclonal |
species reactivity | mouse |
packaging【包装】 | antibody small pack of 25 μg |
concentration【浓度】 | 0.2 mg/mL |
technique(s) | flow cytometry: suitable |
isotype【同位素/亚型】 | IgG2aκ |
UniProt accession no.【UniProt登记号】 | P35461 |
shipped in【运输】 | wet ice |
产品说明
Storage and Stability【储存及稳定性】 | It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | nwg |